Research lines:

• Tuberculosis control (MYC)
• Molecular characterizacion studies of the Mycobacterium avium complex (MYC)
• Tuberculosis diagnosis (MYC)
• Molecular epidemiology of tubeculosis (MYC)
• Diagnosis of other mycobacteriosis (MYC)

Next scientific publications:

• Casal C., Bezos J., Diez-Guerrier A., Alvarez J., Romero B., de Juan L., Rodriguez-Campos S., Vordermeier M., Whelan A., Hewinson RG., Mateos A., Dominguez L. and Aranaz A.. Evaluation of two cocktails containing ESAT-6, CFP-10 and Rv-3615c in the interferon-y assay for diagnosis of bovine tuberculosis. Preventive Veterinary Medicine, 105(1-2):149-154.
• Rodriguez-Campos S., Schürch AC., Dale J., Lohan AJ., Cunha MV., Botelho A., De Cruz K., Boschiroli ML., Boniotti B., Pacciarini M., Garcia-Pelayo MC., Romero B., de Juan L., Dominguez L., Gordon SV., van Soolingen D., Loftus B., Berg S., Hewinson RG., Aranaz A. and Smith NH.. European 2-a clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases , 12(4):866-872.
• Rodriguez-Campos S., Gonzalez S., de Juan L., Romero B., Bezos J., Casal C., Alvarez J., Fernandez de Mera IG., Castellanos E., Mateos A., Saez JL., Dominguez L., Aranaz A. and The Spanish Network on Surveillance and Monitoring of Animal Tuberculosis.. A database for animal tuberculosis (mycoDB.es) within the context of the Spanish national programme for eradication of bovine tuberculosis. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases , 12(4):877-882.
• Castellanos E., Aranaz A., de Juan L., Dominguez L., Linedale R. and Bull TJ.. A 16kb naturally occurring genomic deletion including mce and PPE genes in Mycobacterium avium subspecies paratuberculosis isolates from goats with Johne`s disease. Veterinary Microbiology.
• Bezos J., Alvarez J., Moreno I., de Juan L., Romero B., Rodriguez-Campos S., Dominguez M., Torano A., Mateos A., Dominguez L. and Aranaz A.. Study of peripheral blood cell populations involved in the immune response of goats naturally infected with Mycobacterium caprae. Research in Veterinary Science.

Last scientific publications:

• Castellanos E., de Juan L., Dominguez L. and Aranaz A.. Progress in molecular typing of Mycobacterium avium subspecies paratuberculosis. Research in Veterinary Science, 92(2):169-79. 2012.
• Alvarez J., Perez A., Bezos J., Marques S., Grau A., Saez JL., Minguez O., de Juan L. and Dominguez L.. Evaluation of the sensitivity and specificity of bovine tuberculosis diagnostic tests in naturally infected cattle herds using a Bayesian approach. Veterinary Microbiology, 155(1):38-43. 2012.
• Alvarez J., Bezos J., de Juan L., Vordermeier M., Rodriguez-Campos S., Fernandez de Mera IG., Mateos A. and Dominguez L.. Diagnosis of Tuberculosis in Camelids: Old Problems, Current Solutions and Future Challenges. Transboundary and Emerging Diseases, 59(1):1-10. 2012.
• Bezos J., Alvarez J., Romero B., Aranaz A. and de Juan L.. Tuberculosis in goats: Assessment of current in vivo cell-mediated and antibody-based diagnostic assays. The Veterinary Journal, 191(2):161-5. 2012.
• Munoz-Mendoza M., de Juan L., Menendez S., Ocampo A., Mourelo J., Saez JL., Dominguez L., Gortazar C., Garcia-Marin JF. and Balseiro A.. Tuberculosis due to Mycobacterium bovis and Mycobacterium caprae in sheep. The Veterinary Journal, 191(2):267-9. 2012.

Last doctoral thesis supervised:

• Javier Bezos Garrido. Tuberculosis in goats: study of immune response and contributions to diagnosis. 2011.
• Beatriz Romero Martínez. Bovine tuberculosis: molecular epidemiology and implications in Public and Animal Health. 2010. (Premio Laboratorios Ovejero 2011. Premio Extraordinario de Doctorado)
• Elena Castellanos Rizaldos. Molecular characterization of Mycobacterium avium subspecies paratuberculosis isolates. Epidemiological distribution in Spain. 2010. (Premio a la Mejor Tesis de Sanidad Animal 2011 (Syva). Premio Extraordinario de Doctorado)

Last outreach publications:

• Castellanos E., Dominguez L., de Juan L. and Aranaz A.. Paratuberculosis (Johne`s Disease): Clinical Signs, Diagnosis, Lesions, Prophylaxis/Treatment/Control and Zoonotic Potential. Chapter 11, Livestock: Rearing, Farming Practices and Diseases. Ed. 1. Nova Science Pub Inc. 2011.
• Bezos J., Alvarez J., Pieltain MC., de Juan L., Pelaez P., Quesada O., Moreno I., Mateos A., Blazquez JC., Saez JL., Vigo V. and Dominguez L.. Caracterización y eliminación del último caso de tuberculosis en ganado bovino detectado en las Islas Canarias. Aplicación de técnicas rutinarias y complementarias de diagnóstico en la erradicación del último foco. Boletín de Anembe, 91:46-57, Anmbe. 2011.
• Alvarez J., Bezos J., Casal C., Boadella M. and de Juan L.. Micobacteriosis en el porcino: Importancia y pautas para su diagnóstico, identificación y control. Cría y Salud, 35: 40-45, Axón Comunicación. 2011.
• de Juan L.. The fight against bovine TB. International Innovation, December 2010:21-23, Research Media Ltd.. 2010.
• Alvarez J., Marques S., Saez JL., de Juan L., Romero B., Grau A., Mateos A. and Minguez O.. Evaluación de las medidas incorporadas en el programa de erradicación de la tuberculosis bovina de Castilla y León. Editorial Complutense / Centro VISAVET. 2010.

Last communications:

• de Juan L.. El papel de la epidemiología molecular en el control de enfermedades endémicas; Tuberculosis. Curso de Formación sobre Epidemiología Molecular. 2011. (Oral communication)
• Alvarez J., Perez A., Bezos J., Marques S., Grau A., Saez JL., Minguez O., de Juan L., Casal C., Mateos A. and Dominguez L.. Evaluación de pruebas diagnósticas de tuberculosis bovina mediante análisis bayesiano. 1er Congreso Internacional de la Sociedad Iberoamericana de Epidemiología Veterinaria y Medicina Preventiva: enfoques prácticos para la prevención, el control y la erradicación de enfermedades. 2011. (Oral communication)
• Bezos J., Casal C., Romero B., Rodriguez-Campos S., Mateos A., Dominguez L. and de Juan L.. Interference of Corynebacterium pseudotuberculosis with caprine tuberculosis diagnostics tests. AHVLA International Conference 2011. 2011. (Poster communication)
• Casal C., Bezos J., Diez A., Romero B., de Juan L., Alvarez J., Rodriguez-Campos S., Vordermeier M., Whelan A., Hewinson G., Mateos A., Dominguez L. and Aranaz A.. Use of antigenic cocktails in the skin test for in vivo diagnosis of bovine tuberculosis. AHVLA International Conference 2011. 2011. (Poster communication)
• Casal C., Bezos J., Romero B., Diez A., Alvarez J., Rodriguez-Campos S., de Juan L., Mateos A., Linscott R., Martel E., Lawrence J., Aranaz A. and Dominguez L.. Evaluation of a serological assay for the detection of bovine tuberculosis. AHVLA International Conference 2011. 2011. (Poster communication)