Evaluation of the antibody production of a trial on VLP vaccines for bluetongue 1 and 4 serotypes
April 27th, 2009
Perez de Diego AC., Espinosa L. and Sanchez-Vizcaino JM.
Conference in VIII Congreso de Ciencias Veterinarias y Biomedicas
The main purpose of this study was to evaluate by a competitive ELISA test the VP7
antibodies in response to VLPs vaccines for bluetongue serotypes 1 & 1+4, and after the virus
challenge, to assess the humoral immune response produced by these VLPs. The three
vaccinated groups showed positive results 35 days after the vaccination. However, in non
vaccinated animals antibodies were not detected before day 10 post virus challenge.
The presence of antibodies in vaccinated animals implies that VLP Vaccines are able to
stimulate a humoral response
