Clinical study of a trial on VLP vaccine for bluetongue virus serotypes 1 & 1+4 in sheep
April 27th, 2009
Perez de Diego AC., del Carmen P., Carvajal J. and Sanchez-Vizcaino JM.
Oral communication in VIII Congreso de Ciencias Veterinarias y Biomedicas
Bluetongue Virus disease is an infectous disease submitted to a sanitary control composed by
several measures of prevention, and one of these measures is the vaccination of the sensible
species. In the development of vaccines opposite to this disease, a new trend is the production
of polyvalent vaccines by VLP`s technology (virus like particles). This work has had as aim to
value by clinical survey, 2 VLP vaccines, for serotypes 1 and 1+4. The results confirm the
lack of fever, clinical signs and pathologic injuries in vaccinated animals opposite to control
animals, which indicates that these new vaccines protect for the appearance of clinical signs
